Simvastatin belongs to the category of medicine known as HMG- CoA reductase inhibitors. This medicine helps in reducing the level of bad cholesterol and triglycerides in the blood and raises the level of good cholesterol.
Prescribed dose of Simvastatin
- Dose for the prevention of cardiovascular disease: A person should administer a prescribed dose of 5 to 40 mg orally once a day in the evening.
- Dose for treating homozygous familial hypercholesterolemia: A prescribed dose of 40 mg orally once a day in the evening.
Contraindications of Simvastatin
- A person having a history of drug or alcohol addiction should avoid intake of this medicine.
- If you are suffering from the problem of diabetes or thyroid disorder should avoid administration of this medicine.
- In the case of liver or kidney disease, this medicine should not be consumed.
Drug interactions of Simvastatin
- Heart medication such as Amiodarone, Amlodipine, Diltiazem, Dronedarone, Ranolazine, Verapamil.
- Anti- HIV medicine such as Atazanavir, Cobicistat, Darunavir,
- Hepatitis C medications such as Boceprevir, Telaprevir
Intake of Simvastatin may lead to various unwanted ill effects such as headache, constipation, nausea, stomach pain, cold symptoms such as stuffy nose, sneezing, sore throat and difficulty in urination.
Precautions to be followed while administering Simvastatin are:
- Intake of grapefruit or grape juice should be avoided along with this medicine as it may lead to unwanted side effects.
- You should avoid consumption of food products containing fat because this medicine may not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.
- You should avoid consumption of alcohol or any product containing alcohol along with this medicine as it may raise triglyceride levels and may increase your risk of liver damage.