Cardura is marketed in oral preparations that comprise of Doxazosin mesylate as the major working constituent, which belongs to the class of alpha-blocker drug. Thus, Cardura is beneficial in the management of high blood pressure and benign prostate hyperplasia (BPH) with the widening of smooth muscles for an easy supply of blood.
Contradictory indications for the use of Cardura-
- Oversensitivity towards Doxazosin or any other present ingredient in Cardura is an opposing condition.
- Pregnancy, lactation, children and geriatric patients are contraindicated for the use of Cardura.
- Renal or hepatic impairment conditions are not safe and suitable for the use of Cardura medication.
Dosing regimen for Cardura-
1 mg dose of Cardura at bedtime is generally advised for the treatment of hypertension in adults. The dose can be increased after 1-2 week depending on the response. Maintenance dose is 4mg daily and the maximum dose should not be more than 16mg per day.
For the treatment of BPH, the suggested dose is 1 mg one time a day at bedtime. The dose can be increased after 1-2 week. The maintenance dose is 2-4 mg in the day and the maximum should not cross over the dose of 8mg in a day.
Drug interactions with Cardura-
- Diuretic medications
- NSAID drugs
- Other beta-blockers
- Calcium-channel blockers
- ACE inhibitors
Undesirable responses of Cardura-
- Back pain
- Chest pain
- Dry mouth
- Vision change
- Urinary tract infection
Safety precautions with the use of Cardura-
- Monitor blood pressure after 2-6 hours of drug intake.
- Avoid driving and another task that needs consciousness.
- Take precaution if you have undergone any eye surgery for cataract.
- Use of Cardura is should be avoided in case of orthostatic hypotension.